Cell Therapy Yields Promising Results For Scleroderma Treatment PDF Print E-mail
Tuesday, 24 September 2013 08:49
Cytori Therapeutics, Inc. provided preliminary data from a study evaluating a potential treatment for Scleroderma based on the company's cell therapy. The investigator-funded, open-label, pilot study is being conducted on patients with Cutaneous Systemic Scleroderma in France.

12 patients were administered Cytori's cell therapy, injected into their fingers. Safety and hand function improvement are the primary endpoints of the study which were measured by the Cochin hand functional scale at six months.

At the end of the two month follow-up period, no infection, ischemic complications or serious adverse events were observed. Moreover, there was a significant improvement in the Cochin hand function disability scale.

As far as secondary endpoints are concerned, there was a significant improvement in Scleroderma health assessment questionnaire score and in Raynaud's Severity Score. Also, there was a significant improvement in hand pain when measured by the visual analog pain scale.

Cytori is focused primarily on the development of treatments for cardiovascular disease and soft tissue injuries and burns based on its proprietary cell therapy formulation. The company's cell therapy is based on the formulation of stem and regenerative cells derived from a patient's own adipose (fat) tissue (ADRCs).

Source: NASDAQ (2013)
 
More articles :

» Systemic Sclerosis Sine Scleroderma

HADI POORMOGHIM, MARY LUCAS, NOREEN FERTIG, and THOMAS A. MEDSGER, JR.ARTHRITIS & RHEUMATISM Vol. 43, No. 2, February 2000, pp 444–451 © 2000, American College of RheumatologyObjectiveTo describe the demographic, clinical, and laboratory...

» Kidney Involvement In Scleroderma

Kidney disease is one of the manifestations of vascular, or blood vessel involvement, in .Other manifestations of vascular disease in Scleroderma include Raynaud's phenomenon, telangiectasia (dilated blood vessels, most common on the face and...

» Pulsed High-Dose Corticosteroids Combined With Low-Dose Methotrexate in Severe Localized Scleroderma

Alexander Kreuter, MD; Thilo Gambichler, MD; Frank Breuckmann, MD; Sebastian Rotterdam, MD; Marcus Freitag, MD; Markus Stuecker, MD; Klaus Hoffmann, MD; Peter Altmeyer, MDArch Dermatol. 2005;141:847-852Objective: To evaluate the efficacy of pulsed...

» What Is Vitiligo?

According to the Staff, Vitiligo (vit-ih-LI-go) is a condition in which your skin loses , the pigment that determines the color of your skin, hair and eyes. Vitiligo occurs when the cells that produce melanin die or no longer form melanin, causing...

» Georgetown Study: Scleroderma Dramatically Under-diagnosed With Commercial Screening Method

New research from Georgetown University Medical Center (GUMC) suggests that up to 40 percent of patients will not be correctly diagnosed with the disorder using a new automated commercial screening test. The findings of the study will be presented...

» Endothelin Drugs Benefit Those With Pulmonary Hypertension

Breaking news from has reported that recent research to block the effects of endothelin, a powerful substance that constricts blood vessels and stimulates cell growth, has led to successful treatment of and provides hope for treating other chronic...