The Incidence Of Prostate Cancer Higher In Men With Autoimmune Diseases PDF Print E-mail
Monday, 06 May 2013 22:05
Men with autoimmune diseases have a higher incidence of prostate cancer (PCa) than those without those diseases, according to study findings presented at the American Urological Association annual meeting.

Using the National Inpatient Sample database, researchers obtained data on 189,290 men with a history of autoimmune disease—multiple sclerosis (MS), systemic lupus erythematosus (SLE), systemic sclerosis, psoriasis, Sjogren's syndrome, discoid lupus erythematosus (DLE), or rheumatoid arthritis (RA)—and a subsequent diagnosis of PCa.

The investigators, led by Zachary Klaassen, MD, a urology resident at the Medical College of Georgia, Georgia Regents University, in Augusta, compared the age-specific incidence of PCa in this cohort with an external cohort of patients from the Surveillance, Epidemiology and End Results (SEER) database (2000-2009).

Compared with the general population, the incidence of PCa was three times greater for men with MS, five times greater for men with SLE, six times greater for men with systemic sclerosis, seven times greater for men with psoriasis, nine times greater for men with Sjogren's syndrome, 10 times greater for men with DLE, and 10 times greater for men with RA, according to the researchers.
Autoimmune disease affects 3.6 million to 5.9 million men in the U.S., Dr. Klaassen and his colleagues noted.

To their knowledge, the investigators said, their study is the first to suggest an increased incidence of PCa in men with autoimmune diseases.

Dr. Klaassen cautioned that the finding of an increased incidence of PCa may be due to increased screening of patients who, because of their autoimmune disease, may receive more intensive medical follow-up.

Source: Renal & Urology News (2013), "Prostate Cancer Incidence Higher in Men with Autoimmune Disease"; original article can be viewed here.

 
More articles :

» Modulation of Fibrosis in Systemic Sclerosis by Nitric Oxide and Antioxidants

Systemic sclerosis is a multisystem, connective tissue disease of unknown aetiology characterized by vascular dysfunction, autoimmunity, and enhanced fibroblast activity resulting in fibrosis of the skin, heart, and lungs, and ultimately internal...

» Explaining The ANA Blood Test Normal Range

Before knowing what is the ANA blood test normal range and the blood test results meaning, let us . ANA is the abbreviation for the term Anti Nuclear Antibody. An ANA blood test is done in order to determine the presence of anti-nuclear antibodies...

» Sonographic Evaluation of Pediatric Localized Scleroderma Preliminary Disease Assessment Measures

Background: Our earlier work in the ultrasonograpy of localized scleroderma (LS) suggests that altered levels of echogenicity and vascularity can be associated with disease activity. Utrasound is clinically benign and readily available, but can be...

» No Exercise Benefit with Bosentan in Systemic Sclerosis

Treatment with the endothelin receptor antagonist bosentan () failed to improve exercise capacity in patients with systemic sclerosis, a randomized trial found. After one year of treatment, there was a nonsignificant mean change in the six-minute...

» March Designated as 'National Autoimmune Diseases Awareness Month' in the U.S.

On the evening of March 4, 2010, the U.S. Senate passed a resolution designating March as "National Autoimmune Diseases Awareness Month" and supporting efforts to increase awareness of autoimmune diseases and increase funding for autoimmune disease...

» Dog-sled Challenge To Raise Raynaud's Research Cash

Anne Mawdsley has swum with sharks, completed the Olympic bobsleigh run and driven at high speed round a rally course to raise charity cash. But later this month she takes on what could be the biggest challenge of her life - a dog sled run in...

Add comment

Do feel free to leave your comments, as they would add value and knowledge to the community. However, please refrain from making any disparaging, uninformed, or unrelated comments. Thanks :)

Security code
Refresh