| Systemic Sclerosis: An Update on the Aberrant Immune System and Clinical Features |
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| Monday, 06 February 2012 20:12 |
Systemic sclerosis (SSc), or often referred to as Scleroderma (tight skin), is characterized by an exaggerated formation of collagen fibers in the skin, which leads to fibrosis. Accumulating evidence now points toward three pathological hallmarks that are implicated in Ssc, the order of which has yet to be determined: endothelial dysfunction, autoantibody formation, and activation of fibroblasts. This current book, edited by Timothy Radstake, provides current information on the pathogenesis and clinical features of Scleroderma. We, at the Scleroderma Care Foundation, share the hope that this book will aid both clinicians and researchers in dealing with patients with this clinical syndrome. In addition, we hope through its distribution, to shed more light on this rare and severely disabling syndrome, ultimately leading to better research and successful therapeutic targeting. Over two hundred pages of information, we would like to encourage you to download and print your very own copy from the link provided below. |



Systemic sclerosis (SSc), or often referred to as Scleroderma (tight skin), is characterized by an exaggerated formation of collagen fibers in the skin, which leads to fibrosis. Accumulating evidence now points toward three pathological hallmarks that are implicated in Ssc, the order of which has yet to be determined: endothelial dysfunction, autoantibody formation, and activation of fibroblasts.