Morphea Scleroderma PDF Print E-mail
Wednesday, 09 December 2009 14:48
taken from http://dermnetnz.org/immune/img/morph2-s.jpgMorphea, is one of two types of localized Scleroderma, and a disorder characterized by excessive collagen deposits leading to thickening of the dermis, subcutaneous tissues, or both. The cause of Scleroderma is unknown. It is important to remember that it is not contagious, nor inherited or passed on from one generation to the next, except in rare circumstances. We do know that in Scleroderma, the body produces too much of a protein called collagen.

Morphea is classified into plaque, generalized, linear, and deep subtypes according to the clinical presentation and depth of tissue involvement.

Unlike Systemic Sclerosis, Morphea lacks features such as Sclerodactyly, Raynaud's phenomenon, and internal organ involvement. Saleh et al (2009) discussed a new variant, termed Superficial Morphea, which is characterized clinically by hyperpigmented or hypopigmented patches of skin that lack induration.

taken from http://www.lib.uiowa.edu/HARDIN/MD/pictures22/dermnet/morphea61.jpgEarly Morphea Scleroderma has an inflammatory stage, followed by one or more slowly enlarging patches or plaques. These plaques are most commonly oval in shape and vary in size. They have an ivory/yellow center and are surrounded by a violet colored area.

The violet color signifies that the Scleroderma is in a state of activity. The plaques feel firm and hard, but are not deeply bound down. They may be depressed or slightly elevated and are seen more often on the trunk, but may also occur on the face and extremities.

An uncommon form of Morphea is the guttate variety. It is characterized by multiple, small, chalk-white spots which vary in size from 1 to 10mm in diameter. The violet-colored line may surround all or some of the spots and in cases of long duration the line may be brown or grayish. Guttate Morphea primarily involves the chest, neck and shoulders, and only occasionally other parts of the body. Localized Morphea may last from a few months to many years. However, a large proportion of Morphea patients improve spontaneously.

The following are some excellent resources, which have additional information and images on Morphea Scleroderma. You can  read more about treatments, types, and associated complications.

HealthCentral.com (2009), "Morphea Scleroderma". http://www.healthcentral.com/encyclopedia/408/37.html
HealthScout (2009), "Morphea Scleroderma". http://www.healthscout.com/ency/68/37/main.html
EMedicine (2009), "Morphea". http://emedicine.medscape.com/article/1065782-overview
AOCD (2009), "Morphea". http://www.aocd.org/skin/dermatologic_diseases/morphea.html
MayoClinic (2009), "Morphea". http://www.mayoclinic.com/health/morphea/DS00718/DSECTION=symptoms

 
More articles :

» The Science of Raw Food

In a recent article on , we noted that changing your diet and introducing an abundance of living and raw foods provide a much safer alternative than traditional medicine in restoring the body’s alkalinity, and subsequently ensuring good health....

» Scleroderma Drug In Development

According to , has partnered with , the health care investment arm of Morgan Keegan and Co. Inc., to jump-start a capital campaign to raise $12 million to $15 million. ArGentis shelved the campaign last year when the economy soured.The money will...

» What Is Scleroderma?

DefinitionDerived from the Greek words “sklerosis,” meaning hardness, and “derma,” meaning skin, Scleroderma literally means hard skin. Although it is often referred to as if it were a single disease, Scleroderma is really a symptom of a...

» UTHealth Scientists Closing In On Genes Tied To Scleroderma

A new study designed to test suspected links between genes and two immune disorders could open the door to better ways to diagnose and treat the conditions that affect a combined total of approximately 2.5 million people in the United States, report...

» Juvenile Localized Scleroderma: Fewer Flares With Methotrexate

was an effective and well-tolerated treatment for in a randomized, double-blind, placebo-controlled trial involving 70 patients with active disease. At the end of the 12-month study, 31 of 46 patients randomized to receive methotrexate had...

» Modulation of Fibrosis in Systemic Sclerosis by Nitric Oxide and Antioxidants

Systemic sclerosis is a multisystem, connective tissue disease of unknown aetiology characterized by vascular dysfunction, autoimmunity, and enhanced fibroblast activity resulting in fibrosis of the skin, heart, and lungs, and ultimately internal...