Morphea Scleroderma PDF Print E-mail
Wednesday, 09 December 2009 14:48
taken from http://dermnetnz.org/immune/img/morph2-s.jpgMorphea, is one of two types of localized Scleroderma, and a disorder characterized by excessive collagen deposits leading to thickening of the dermis, subcutaneous tissues, or both. The cause of Scleroderma is unknown. It is important to remember that it is not contagious, nor inherited or passed on from one generation to the next, except in rare circumstances. We do know that in Scleroderma, the body produces too much of a protein called collagen.

Morphea is classified into plaque, generalized, linear, and deep subtypes according to the clinical presentation and depth of tissue involvement.

Unlike Systemic Sclerosis, Morphea lacks features such as Sclerodactyly, Raynaud's phenomenon, and internal organ involvement. Saleh et al (2009) discussed a new variant, termed Superficial Morphea, which is characterized clinically by hyperpigmented or hypopigmented patches of skin that lack induration.

taken from http://www.lib.uiowa.edu/HARDIN/MD/pictures22/dermnet/morphea61.jpgEarly Morphea Scleroderma has an inflammatory stage, followed by one or more slowly enlarging patches or plaques. These plaques are most commonly oval in shape and vary in size. They have an ivory/yellow center and are surrounded by a violet colored area.

The violet color signifies that the Scleroderma is in a state of activity. The plaques feel firm and hard, but are not deeply bound down. They may be depressed or slightly elevated and are seen more often on the trunk, but may also occur on the face and extremities.

An uncommon form of Morphea is the guttate variety. It is characterized by multiple, small, chalk-white spots which vary in size from 1 to 10mm in diameter. The violet-colored line may surround all or some of the spots and in cases of long duration the line may be brown or grayish. Guttate Morphea primarily involves the chest, neck and shoulders, and only occasionally other parts of the body. Localized Morphea may last from a few months to many years. However, a large proportion of Morphea patients improve spontaneously.

The following are some excellent resources, which have additional information and images on Morphea Scleroderma. You can  read more about treatments, types, and associated complications.

HealthCentral.com (2009), "Morphea Scleroderma". http://www.healthcentral.com/encyclopedia/408/37.html
HealthScout (2009), "Morphea Scleroderma". http://www.healthscout.com/ency/68/37/main.html
EMedicine (2009), "Morphea". http://emedicine.medscape.com/article/1065782-overview
AOCD (2009), "Morphea". http://www.aocd.org/skin/dermatologic_diseases/morphea.html
MayoClinic (2009), "Morphea". http://www.mayoclinic.com/health/morphea/DS00718/DSECTION=symptoms

 
More articles :

» New Site For Adult Stem Cell Resources Launched

A new website is detailing success stories in adult stem cell research. is part of a campaign to educate and spread awareness about the potentials and successes of adult stem cell therapies, and was created by the Family Research Council and...

» Development of an Activity Index for Localized Scleroderma (Morphea)

E. Lanciano, A. CHIALà, E. Praino, V. Grattagliano, M. Covelli, F. Iannone, G. Lapadula Reumatologia Universitaria, Policlinico, Bari, ItalyAnn Rheum Dis 2011;70(Suppl3):481Background: Morphea is a skin disorder characterized by fibrosis. It...

» Capillary Regeneration in Scleroderma: Stem Cell Therapy Reverses Phenotype?

Jo N. Fleming, Richard A. Nash, D. O. McLeod, David F. Fiorentino, Howard M. Shulman, M. Kari Connolly, Jerry A. Molitor, GretchenHenstorf, Robert Lafyatis, David K. Pritchard, Lawrence D. Adams, Daniel E. Furst, Stephen M....

» Italians Explain Low Sex Drive In Female Scleroderma Patients

In a world first, Italian rheumatologists have discovered why women living with Systemic Sclerosis often suffer from a low sex drive. The study of 22 women with systemic sclerosis found the disease resulted in a lack of blood flow around the...

» Scientists and Clinicians Address Diagnosis and Treatment for Autoimmune and Autoinflammatory Diseases

Autoimmune and autoinflammatory diseases are a major health issue. The National Institutes of Health reports that up to 23.5 million Americans are afflicted. The American Autoimmune Related Diseases Association reports the number is closer to 50...

» The Incidence Of Prostate Cancer Higher In Men With Autoimmune Diseases

Men with autoimmune diseases have a higher incidence of (PCa) than those without those diseases, according to study findings presented at the annual meeting.Using the National Inpatient Sample database, researchers obtained data on 189,290 men...